Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenolsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonic Acid SCHEMBL11202643 | 0.97 | LMNA (0.56) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL8008849 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL15023824 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL2518118 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL11084143 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL125056 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL1470053 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL119165 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL11196801 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL18577736 | 0.94 | LMNA (0.59) | LMNACA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073802-A | Process for the preparation and purification of 3-(4-lithiosulfophenoxy)-1,2-propanediol | ICI AMERICAS INC. (US) | 1978-02-14 | — | — | US | claimed |
| CN-113582930-A | Preparation method of 4, 5-dicyano-2-trifluoromethyl-imidazole salt | 如鲲(山东)新材料科技有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-9718905-B2 | Polythiophene, water-soluble electrically conductive polymer using it, and method for producing it | TOSOH CORPORATION (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20150337061-A1 | POLYTHIOPHENE, WATER-SOLUBLE ELECTRICALLY CONDUCTIVE POLYMER USING IT, AND METHOD FOR PRODUCING IT | TOSOH CORPORATION (JP) | 2015-11-26 | — | — | US | disclosed |
| CN-103044348-B | Benzoxazine resin containing sulfonic group, and preparation method and application thereof | UNIV SHANDONG | 2014-12-17 | — | — | CN | disclosed |
| CN-103044348-A | Benzoxazine resin containing sulfonic group, and preparation method and application thereof | UNIV SHANDONG | 2013-04-17 | — | — | CN | disclosed |
| CN-1202169-C | Thermoplastic resin composition and product thereof | UNIV SHANDONG (CN) | 2005-05-18 | — | — | CN | disclosed |
| CN-1448437-A | Thermoplastic resin composition and product thereof | UNIV SHANDONG (CN) | 2003-10-15 | — | — | CN | disclosed |
| EP-0517511-B1 | Process for the preparation of polyester, and its composition | POLYPLASTICS CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5302690-A | Catalytic transesterification | POLYPLASTICS CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0517511-A2 | Process for the preparation of polyester, and its composition | POLYPLASTICS CO. LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-4073802-A | Process for the preparation and purification of 3-(4-lithiosulfophenoxy)-1,2-propanediol | ICI AMERICAS INC. (US) | 1978-02-14 | — | — | US | disclosed |