Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenolsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.56 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.56 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.56 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.46 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonic Acid SCHEMBL125056 | 1.00 | LMNA (0.59) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL30756570 | 1.00 | LMNA (0.59) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL1642911 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL710820 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL8764688 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL27472854 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL11198896 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL7671608 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL10758562 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL11202643 | 0.97 | LMNA (0.56) | LMNACA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57085846-A | — | — | None | — | — | JP | disclosed |
| JP-3074458-A | — | — | None | — | — | JP | disclosed |
| JP-57207639-A | — | — | None | — | — | JP | disclosed |
| JP-57198743-A | — | — | None | — | — | JP | disclosed |
| CN-117729943-A | Iron (III) macrocyclic complexes with mixed hydroxyl side groups as MRI contrast agents | 纽约州立大学研究基金会 | 2024-03-19 | — | — | CN | disclosed |
| US-8889768-B2 | Laser-transparent PBT with organic additives | BASF SE (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110251171-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BACH ANDREW THOMAS | 2011-10-13 | — | — | US | disclosed |
| US-20100152255-A1 | Organic Compounds | DAMON ROBERT EDSON | 2010-06-17 | — | — | US | disclosed |
| US-7700637-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-04-20 | — | — | US | disclosed |
| US-7538135-B2 | Benzenesulfonylamino compounds and pharmaceutical compositions containing these compounds | NOVARTIS AG (CH) | 2009-05-26 | — | — | US | disclosed |
| EP-0166571-A2 | Peracid and bleach activator compounds and use thereof in cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4539130-A | SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0150532-A1 | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4486327-A | FOR PEROXYGEN COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-4483778-A | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |
| US-4390493-A | SULFONATES, HYDROXY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-06-28 | — | — | US | disclosed |
| JP-S57207639-A | BLOW MOLDED POLYESTER ARTICLE | ASAHI CHEM IND CO LTD | 1982-12-20 | — | — | JP | disclosed |
| JP-S57198743-A | POLYESTER COMPOSITION | ASAHI CHEM IND CO LTD | 1982-12-06 | — | — | JP | disclosed |
| JP-S5785846-A | POLYESTER COMPOSITION | ASAHI CHEM IND CO LTD | 1982-05-28 | — | — | JP | disclosed |
| US-4154753-A | SURFACTANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152255-A1 | Organic Compounds | PPARG, FABP2, PPARA | CA2 3311/4885CA12 4508/4885CA1 4431/4885 |
| US-20110251171-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | PPARG, PPARA, PPARD | CA2 3234/4885CA12 4606/4885CA1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.