Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782060 | 0.88 | MRGPRX4 (0.47) | MRGPRX4FFAR4FFAR1FOLH1MAPT | |
| SCHEMBL8101220 | 0.87 | RXRA (0.47) | SGMS2TP53HTTPTGDR2FOLH1 | |
| SCHEMBL8782034 | 0.85 | MRGPRX4 (0.55) | MRGPRX4FFAR4FFAR1TP53HTT | |
| SCHEMBL8782322 | 0.84 | FFAR4 (0.48) | MRGPRX4FFAR4FFAR1FOLH1 | |
| SCHEMBL8782203 | 0.84 | MRGPRX4 (0.52) | MRGPRX4SGMS2FFAR4FFAR1TP53 | |
| Toluene SCHEMBL28735228 | 0.82 | RXRA (0.46) | MRGPRX4SGMS2TP53HTTPTGDR2 | |
| SCHEMBL8782015 | 0.82 | HTT (0.47) | MRGPRX4SGMS2TP53HTTFOLH1 | |
| SCHEMBL8783068 | 0.80 | TP53 (0.48) | MRGPRX4SGMS2TP53HTTPTGDR2 | |
| SCHEMBL8782268 | 0.80 | NR4A2 (0.48) | MRGPRX4MEN1KMT2A | |
| SCHEMBL8782010 | 0.79 | FFAR1 (0.46) | FFAR4FFAR1TP53HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718279-B1 | Process for the preparation of o-substituted benzoylcyanides | BASF AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| EP-0718279-A1 | Process for the preparation of o-substituted benzoylcyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-26 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |