Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783068 | 0.84 | TP53 (0.48) | HTTTP53MRGPRX4SGMS2ALDH1A1 | |
| SCHEMBL8782010 | 0.83 | FFAR1 (0.46) | HTTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL8101220 | 0.83 | RXRA (0.47) | HTTTP53SGMS2ALDH1A1MAPT | |
| SCHEMBL8782020 | 0.83 | TP53 (0.69) | HTTTP53MRGPRX4NPC1SGMS2 | |
| SCHEMBL9442060 | 0.82 | RXRA (0.50) | HTTTP53MRGPRX4SGMS2ALDH1A1 | |
| SCHEMBL8782006 | 0.82 | MRGPRX4 (0.49) | HTTTP53MRGPRX4SGMS2MEN1 | |
| SCHEMBL8782250 | 0.81 | HTT (0.54) | HTTTP53MRGPRX4NPC1SGMS2 | |
| SCHEMBL8594751 | 0.81 | ALDH1A1 (0.46) | HTTTP53MRGPRX4NPC1SGMS2 | |
| SCHEMBL8594755 | 0.81 | ALDH1A1 (0.46) | HTTTP53MRGPRX4NPC1SGMS2 | |
| SCHEMBL8069191 | 0.79 | KDM4E (0.48) | HTTTP53NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718279-B1 | Process for the preparation of o-substituted benzoylcyanides | BASF AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| EP-0718279-A1 | Process for the preparation of o-substituted benzoylcyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-26 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |