Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781962 | 0.84 | LOXL2 (0.47) | — | |
| SCHEMBL8782221 | 0.83 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL9668871 | 0.82 | ALDH1A1 (0.39) | KMT2A | |
| SCHEMBL8782005 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1 | |
| SCHEMBL9572453 | 0.82 | MEN1 (0.53) | KMT2AMEN1 | |
| SCHEMBL28459807 | 0.78 | KMT2A (0.44) | KMT2AMEN1 | |
| SCHEMBL8781965 | 0.78 | MEN1 (0.53) | ACHEGRM4KMT2AMEN1 | |
| SCHEMBL8781981 | 0.77 | MEN1 (0.34) | KMT2AMEN1 | |
| SCHEMBL9354128 | 0.75 | LOXL2 (0.48) | — | |
| SCHEMBL15881349 | 0.74 | MEN1 (0.48) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504799-B1 | Mixted pyridine-2,4- and 2,5-dicarboxylic acid diamides, process for their preparation, their use as well as medicaments based on these compounds | HOECHST AG (DE) | 1997-07-02 | — | — | EP | disclosed |
| EP-0504799-A1 | Mixted pyridine-2,4- and 2,5-dicarboxylic acid diamides, process for their preparation, their use as well as medicaments based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-23 | — | — | EP | disclosed |