Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14481040 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL14481065 | 0.87 | KDM4E (0.40) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL8641 | 0.87 | KDM4E (0.40) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL14481180 | 0.84 | CHRNA7 (0.45) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL721449 | 0.81 | OPRK1 (0.40) | ALDH1A1MAPTKDM4EPOLBHSD17B10 | |
| SCHEMBL14481042 | 0.80 | PIK3CD (0.41) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL14481043 | 0.80 | PIK3CD (0.41) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL2115940 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL2115939 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL2117487 | 0.79 | OPRK1 (0.38) | ALDH1A1LMNAMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499129-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011058108-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2011-05-19 | — | — | WO | disclosed |