Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783164 | 0.82 | TDP1 (0.39) | ABCG2TDP1PPARAPPARGLTA4H | |
| SCHEMBL8783143 | 0.79 | ABCG2 (0.35) | ABCG2NPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL8783155 | 0.78 | NPSR1 (0.41) | ABCG2NPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL9429885 | 0.77 | ABCG2 (0.40) | ABCG2NPC1RAB9AL3MBTL1NPSR1 | |
| SCHEMBL7344950 | 0.76 | ABCG2 (0.39) | ABCG2NPC1RAB9AL3MBTL1NPSR1 | |
| SCHEMBL5389049 | 0.76 | TDP1 (0.37) | NPC1RAB9AL3MBTL1TDP1PPARA | |
| SCHEMBL5394050 | 0.75 | TDP1 (0.40) | RAB9AL3MBTL1TDP1LTA4HCYP2D6 | |
| SCHEMBL9430303 | 0.74 | AGTR1 (0.41) | ABCG2NPC1RAB9AL3MBTL1NPSR1 | |
| SCHEMBL8783257 | 0.74 | TDP1 (0.36) | ABCG2NPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL9431379 | 0.73 | AGTR1 (0.39) | ABCG2NPC1RAB9AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760814-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032961-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |