Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983929 | 0.91 | TDP1 (0.36) | TDP1NPSR1RECQLLTA4HSLC6A3 | |
| SCHEMBL5394050 | 0.90 | TDP1 (0.40) | TDP1LTA4HSLC6A3RAB9ATP53 | |
| SCHEMBL5389044 | 0.77 | ESR1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8783148 | 0.76 | ABCG2 (0.39) | TDP1NPSR1RECQLLTA4HSLC6A3 | |
| SCHEMBL5389054 | 0.74 | MEN1 (0.39) | NPSR1RECQLLTA4HSLC6A3NPC1 | |
| SCHEMBL4990435 | 0.72 | SMN1; SMN2 (0.36) | NPSR1RECQLNPC1RAB9AL3MBTL1 | |
| SCHEMBL8783164 | 0.71 | TDP1 (0.39) | TDP1LTA4HSLC6A3MEN1KMT2A | |
| SCHEMBL8783257 | 0.68 | TDP1 (0.36) | TDP1LTA4HSLC6A3NPC1RAB9A | |
| SCHEMBL5400790 | 0.68 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL5983933 | 0.66 | MEN1 (0.40) | NPSR1RECQLLTA4HSLC6A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007501770-A | — | — | 2007-02-01 | — | — | JP | claimed |
| EP-1660463-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | Dipharma S.p.A. (IT) | 2006-05-31 | — | — | EP | claimed |
| WO-2005014560-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | DIPHARMA S.P.A. (IT) | 2005-02-17 | — | — | WO | claimed |
| EP-1660463-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | Dipharma S.p.A. (IT) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014560-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | DIPHARMA S.P.A. (IT) | 2005-02-17 | — | — | WO | disclosed |