Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416442 | 0.90 | POLB (0.34) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL8927423 | 0.88 | MEN1 (0.43) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL8782775 | 0.87 | MEN1 (0.35) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL8783548 | 0.86 | ALDH1A1 (0.32) | POLBKCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL9227704 | 0.80 | MEN1 (0.38) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9694106 | 0.79 | ALDH1A1 (0.42) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL9416431 | 0.79 | KCNH2 (0.36) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9416448 | 0.79 | MEN1 (0.35) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9694523 | 0.78 | KDM4E (0.46) | TOP2ATOP2BALDH1A1 | |
| SCHEMBL9145961 | 0.78 | MEN1 (0.46) | POLBCACNA1FMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607826-B1 | Fluoro-trifluoromethylbenzoic acid derivatives | BAYER AG (DE) | 1997-05-07 | — | — | EP | disclosed |
| EP-0607826-A1 | Fluoro-Trifluoromethylbenzoic acid derivatives | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |