Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784161 | 0.82 | BRS3 (0.39) | BRS3 | |
| SCHEMBL7501755 | 0.79 | EDNRA (0.44) | BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL8435187 | 0.73 | EDNRA (0.44) | BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL7502700 | 0.72 | EDNRA (0.43) | BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL7506559 | 0.72 | BRS3 (0.40) | BRS3KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL6588042 | 0.72 | BRS3 (0.40) | BRS3KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8434768 | 0.71 | EDNRA (0.52) | BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL8431751 | 0.70 | EDNRA (0.48) | BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL6577534 | 0.69 | EDNRA (0.36) | BRS3CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL7495951 | 0.69 | EDNRA (0.46) | BRS3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-A1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1997-06-04 | — | — | EP | disclosed |