Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506559 | 0.91 | BRS3 (0.40) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580054 | 0.87 | BRS3 (0.39) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6581992 | 0.87 | MEN1 (0.42) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6579920 | 0.84 | EDNRA (0.46) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8524654 | 0.84 | SMN1; SMN2 (0.39) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580022 | 0.84 | BRS3 (0.43) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6579951 | 0.84 | SMN1; SMN2 (0.41) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6577534 | 0.83 | EDNRA (0.36) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580198 | 0.82 | EDNRA (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL8784081 | 0.82 | MAPK1 (0.41) | BRS3KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804435-B1 | NOVEL IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2004-03-10 | — | — | EP | disclosed |