Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.37 |
| ▸ | GABRE | P78334 | 3/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5763600 | 0.84 | FFAR3 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27628956 | 0.84 | GABRP (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL83334 | 0.83 | — | — | |
| SCHEMBL6529739 | 0.83 | TRIM24 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Benzene SCHEMBL28416065 | 0.80 | HTR2C (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hypochlorous Acid SCHEMBL27560202 | 0.80 | — | — | |
| SCHEMBL25405068 | 0.80 | HIF1A (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Water SCHEMBL757242 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2245157 | 0.80 | — | — | |
| SCHEMBL8994598 | 0.80 | TRIM24 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793663-A1 | (THIOPHEN-2-YL)-PIPERIDIN OR TETRAHYDROPYRIDIN CARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5610164-A | (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| CN-1142498-A | (Thiophen-2-yl-)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PROD (US) | 1997-02-12 | — | — | CN | disclosed |
| EP-0755932-A1 | (Thiophen-2-yl)piperidin or tetrahydropyridin-azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5525600-A | COMPOUND USEFUL AS ANTIPSYCHOTIC, ANTIDEPRESSANT AND ANXIBLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996016961-A1 | (THIOPHEN-2-YL)-PIPERIDIN OR TETRAHYDROPYRIDIN CARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-06 | — | — | WO | disclosed |