Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.37 |
| ▸ | GABRE | P78334 | 3/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528310 | 0.87 | HTR2C (0.32) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL27720658 | 0.85 | PNMT (0.38) | FFAR3LCKFYNGABRPGABRD | |
| SCHEMBL27628956 | 0.84 | GABRP (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Carbamic Acid SCHEMBL8784197 | 0.84 | ACHE (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Pivalate SCHEMBL17956856 | 0.83 | TSHR (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propionic Acid SCHEMBL19873854 | 0.83 | FFAR3 (0.46) | FFAR3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6529739 | 0.83 | TRIM24 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL27911516 | 0.83 | — | — | |
| SCHEMBL83334 | 0.83 | — | — | |
| Benzene SCHEMBL28416065 | 0.80 | HTR2C (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137720-A2 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. (US) | 2024-06-27 | — | — | WO | claimed |
| CN-111954571-B | Poly (arylpiperidinium) polymers including those having stable cationic pendant groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2023-08-04 | — | — | CN | claimed |
| US-11512156-B2 | Poly(aryl piperidinium) polymers including those with stable cationic pendant groups for use as anion exchange membranes and ionomers | UNIVERSITY OF DELAWARE (US) | 2022-11-29 | — | — | US | claimed |
| US-20210009726-A1 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | UNIVERSITY OF DELAWARE | 2021-01-14 | — | — | US | claimed |
| CN-111954571-A | Poly (arylpiperidinium) polymers including those having stable cationic side groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2020-11-17 | — | — | CN | claimed |
| EP-3687671-A2 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | Yan, Yushan (US) | 2020-08-05 | — | — | EP | claimed |
| CN-118546339-A | Polyarylpiperidine electrolyte material containing fluorocarbon main chain and application thereof | 广东鸣洋科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240246070-A1 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. | 2024-07-25 | — | — | US | disclosed |
| WO-2024137720-A2 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-111954571-B | Poly (arylpiperidinium) polymers including those having stable cationic pendant groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2023-08-04 | — | — | CN | disclosed |
| US-11512156-B2 | Poly(aryl piperidinium) polymers including those with stable cationic pendant groups for use as anion exchange membranes and ionomers | UNIVERSITY OF DELAWARE (US) | 2022-11-29 | — | — | US | disclosed |
| US-20210009726-A1 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | UNIVERSITY OF DELAWARE | 2021-01-14 | — | — | US | disclosed |
| CN-111954571-A | Poly (arylpiperidinium) polymers including those having stable cationic side groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2020-11-17 | — | — | CN | disclosed |
| EP-3687671-A2 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | Yan, Yushan (US) | 2020-08-05 | — | — | EP | disclosed |
| CN-103748087-A | Indazole- and pyrrolopyridine-derivative and pharmaceutical use thereof | DAINIPPON SUMITOMO PHARMA CO | 2014-04-23 | — | — | CN | disclosed |
| CN-1976707-A | 3-aminocyclopentanecarboxamides as chemokine receptor modulators | INCYTE CORP (US) | 2007-06-06 | — | — | CN | disclosed |
| EP-1539734-B1 | PIPERIDINE QUINOLYL PROPYL DERIVATIVES AND USE THEREOF AS ANTIMICROBIAL AGENTS | NOVEXEL (FR) | 2006-03-08 | — | — | EP | disclosed |
| EP-1539734-A1 | PIPERIDINE QUINOLYL PROPYL DERIVATIVES AND USE THEREOF AS ANTIMICROBIAL AGENTS | Aventis Pharma S.A. (FR) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024713-A1 | PIPERIDINE QUINOLYL PROPYL DERIVATIVES AND USE THEREOF AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2004-03-25 | — | — | WO | disclosed |