Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547199 | 0.89 | AR (0.48) | ALDH1A1LMNAARENPP2FFAR1 | |
| SCHEMBL11034783 | 0.88 | KDM4E (0.49) | ALDH1A1PPARGPPARAENPP2FFAR1 | |
| SCHEMBL30641469 | 0.86 | FFAR1 (0.47) | ALDH1A1FDFT1ENPP2FFAR1FFAR4 | |
| SCHEMBL191669 | 0.86 | FFAR1 (0.47) | ALDH1A1FDFT1ENPP2FFAR1FFAR4 | |
| SCHEMBL10547112 | 0.86 | KMO (0.51) | ALDH1A1PPARGPPARAFDFT1ENPP2 | |
| SCHEMBL10547235 | 0.84 | ALDH1A1 (0.51) | ALDH1A1PPARGPPARALMNAFDFT1 | |
| SCHEMBL8597193 | 0.84 | AR (0.50) | ALDH1A1LMNAARMAPT | |
| SCHEMBL10550577 | 0.84 | FFAR4 (0.49) | ALDH1A1FDFT1ENPP2FFAR1FFAR4 | |
| SCHEMBL10545623 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1ARENPP2 | |
| SCHEMBL8454764 | 0.84 | NPSR1 (0.43) | ALDH1A1ENPP2FFAR1FFAR4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0091208-B1 | METHOD FOR COMBATING INSECT PESTS, AND NOVEL CYCLOPROPANE CARBOXYLATES USEFUL AS ACTIVE INGREDIENTS THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-06-18 | — | — | EP | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0091208-A1 | Method for combating insect pests, and novel cyclopropane carboxylates useful as active ingredients therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4299839-A | Novel pesticides and pesticidal compositions cyclopropanecarboxylates and pesticidal method | KURARAY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4277490-A | Insecticidal 1-(2-naphthyl)-cyclobutane carboxylate | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-07-07 | — | — | US | disclosed |
| EP-0002620-A1 | Cycloalkyl carboxylic esters, insecticidal compositions containing them, and methods for their preparation | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1979-06-27 | — | — | EP | disclosed |