Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 7/20 | 0.52 |
| ▸ | HTR1B | P28222 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784407 | 0.93 | HTR1D (0.60) | HTR1DHTR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8097614 | 0.81 | KDM4E (0.58) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL8785321 | 0.80 | HTR2C (0.52) | HTR1DHTR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2926854 | 0.79 | KDM4E (0.67) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL8090606 | 0.79 | KDM4E (0.54) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL8474262 | 0.79 | KDM4E (0.56) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL8508491 | 0.78 | KDM4E (0.68) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL8686333 | 0.77 | KDM4E (0.57) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL25072243 | 0.77 | MTNR1A (0.65) | KDM4EATMHTR1DHTR1BCYP1A2 | |
| SCHEMBL30877857 | 0.77 | KDM4E (0.67) | KDM4EATMHTR1DHTR1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497512-B1 | Imidazole, triazole and tetrazole derivatives | MERCK SHARP & DOHME (GB) | 1997-09-24 | — | — | EP | disclosed |