Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.45 |
| ▸ | EDNRB | P24530 | 3/20 | 0.42 |
| ▸ | BRS3 | P32247 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434873 | 0.92 | EDNRA (0.45) | EDNRAEDNRBBRS3KDM4EALDH1A1 | |
| SCHEMBL7495951 | 0.86 | EDNRA (0.46) | EDNRAEDNRBBRS3KDM4EALDH1A1 | |
| SCHEMBL8431736 | 0.85 | BRS3 (0.42) | EDNRABRS3KDM4EALDH1A1HPGD | |
| SCHEMBL7501396 | 0.83 | EDNRA (0.45) | EDNRAEDNRBBRS3KDM4EALDH1A1 | |
| SCHEMBL8784280 | 0.83 | EDNRA (0.43) | EDNRAEDNRBBRS3KDM4EALDH1A1 | |
| SCHEMBL6580208 | 0.82 | EDNRB (0.45) | EDNRAEDNRBBRS3 | |
| SCHEMBL3839001 | 0.81 | EDNRA (0.45) | EDNRAEDNRBBRS3KDM4EALDH1A1 | |
| SCHEMBL7496916 | 0.81 | EDNRA (0.54) | EDNRAEDNRBBRS3 | |
| SCHEMBL6580278 | 0.79 | EDNRA (0.45) | EDNRAEDNRBKDM4EALDH1A1HPGD | |
| SCHEMBL7502700 | 0.79 | EDNRA (0.43) | EDNRAEDNRBBRS3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-A1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1997-06-04 | — | — | EP | disclosed |