Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.64 |
| ▸ | HTR1D | P28221 | 2/20 | 0.64 |
| ▸ | HTR1B | P28222 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 12/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | HTR1F | P30939 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785561 | 0.81 | HTR1A (0.65) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL5752140 | 0.81 | HTR1A (0.71) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8113317 | 0.80 | HTR1A (0.60) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8868836 | 0.80 | HTR1A (0.71) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL22612481 | 0.79 | HTR1A (1.00) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL31574201 | 0.79 | HTR1A (1.00) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8785771 | 0.78 | HTR1A (1.00) | HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6942950 | 0.78 | HTR1A (0.64) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL1121941 | 0.78 | HTR1A (0.76) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL13653014 | 0.78 | HTR1A (0.81) | HTR1AHTR1DHTR1BHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497512-B1 | Imidazole, triazole and tetrazole derivatives | MERCK SHARP & DOHME (GB) | 1997-09-24 | — | — | EP | claimed |