Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.71 |
| ▸ | HTR2C | P28335 | 11/20 | 0.67 |
| ▸ | HTR1D | P28221 | 4/20 | 0.64 |
| ▸ | HTR1B | P28222 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR1E | P28566 | 2/20 | 0.58 |
| ▸ | HTR1F | P30939 | 2/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.58 |
| ▸ | HTR5A | P47898 | 2/20 | 0.58 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796580 | 0.85 | HTR1A (0.56) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL7843588 | 0.84 | HTR1A (0.50) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL8784258 | 0.81 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8784288 | 0.81 | HTR1A (0.64) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8783632 | 0.80 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8868836 | 0.80 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8899999 | 0.80 | HTR1A (0.67) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8783635 | 0.79 | HTR1D (0.60) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL22612481 | 0.79 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL31574201 | 0.79 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527053-B8 | PROCESS FOR PREPARING RIZATRIPTAN | INKE SA (ES) | 2006-03-08 | — | — | EP | disclosed |
| EP-1527053-A1 | PROCESS FOR PREPARING RIZATRIPTAN | VITA CIENTIFICA, S.L. (ES) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004014877-A1 | PROCESS FOR PREPARING RIZATRIPTAN | VITA CIENTIFICA, S.L. (ES) | 2004-02-19 | — | — | WO | disclosed |