Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784352 | 1.00 | FKBP1A (0.35) | FKBP1AALDH1A1HSD17B10EPHX2TSHR | |
| SCHEMBL8711215 | 0.78 | FKBP1A (0.31) | FKBP1A | |
| SCHEMBL8708864 | 0.77 | TSHR (0.39) | EPHX2TSHRSIRT2 | |
| SCHEMBL8708861 | 0.77 | TSHR (0.39) | EPHX2TSHRSIRT2 | |
| SCHEMBL8708555 | 0.76 | CA12 (0.33) | ALDH1A1EPHX2TSHRSIRT2 | |
| SCHEMBL8708554 | 0.76 | CA12 (0.33) | ALDH1A1EPHX2TSHRSIRT2 | |
| SCHEMBL30258011 | 0.73 | TSHR (0.38) | FKBP1AALDH1A1HSD17B10EPHX2TSHR | |
| SCHEMBL9061555 | 0.71 | — | — | |
| SCHEMBL20168030 | 0.68 | TSHR (0.46) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL697966 | 0.68 | TSHR (0.50) | ALDH1A1HSD17B10EPHX2TSHRKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784624-A1 | PURINE AND GUANINE COMPOUNDS AS INHIBITORS OF PNP | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011200-A1 | PURINE AND GUANINE COMPOUNDS AS INHIBITORS OF PNP | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |