Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437393 | 0.83 | KCNN4 (0.46) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL265970 | 0.80 | MEN1 (0.41) | KMT2AGAAMEN1NPC1RAB9A | |
| SCHEMBL6439696 | 0.79 | CYP1A2 (0.40) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6435352 | 0.79 | KCNN4 (0.39) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6437211 | 0.76 | ALDH1A1 (0.37) | KCNN4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL4114605 | 0.75 | ALDH1A1 (0.38) | KMT2ACYP2C19MEN1NPC1RAB9A | |
| SCHEMBL1455027 | 0.74 | HDAC3 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1455028 | 0.74 | HDAC3 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1455851 | 0.74 | HDAC3 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3786557 | 0.74 | CYP2C19 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |