Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516641 | 0.85 | GPR52 (0.34) | ALDH1A1NPC1RAB9AHCAR2KMT2A | |
| SCHEMBL6435352 | 0.83 | KCNN4 (0.39) | ALDH1A1KMT2AL3MBTL1TDP1MEN1 | |
| SCHEMBL6437211 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL28532191 | 0.78 | NPC1 (0.50) | ALDH1A1NPC1RAB9AKMT2ASLC6A2 | |
| SCHEMBL6437393 | 0.78 | KCNN4 (0.46) | ALDH1A1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7821065 | 0.77 | CYP2C19 (0.42) | ALDH1A1NPC1RAB9AHCAR2KMT2A | |
| SCHEMBL8784381 | 0.75 | KCNN4 (0.40) | ALDH1A1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL27369729 | 0.75 | ADH1B (0.38) | ALDH1A1KMT2APTPN1ADH1BADH1C | |
| SCHEMBL6439696 | 0.74 | CYP1A2 (0.40) | ALDH1A1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL10922628 | 0.72 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AHCAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036525-A1 | Non-Natural Amino Acid Derivatives | POXIMAGEN LTD. (GB) | 2009-02-05 | — | — | US | disclosed |
| EP-1981839-A1 | NON-NATURAL AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007091018-A1 | NON-NATURAL AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036525-A1 | Non-Natural Amino Acid Derivatives | CHRNA6, PARK7, CHRNA7 | ALDH1A1 3774/4885NPC1 3699/4885RAB9A 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.