Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563555 | 0.80 | CA1 (0.49) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| Phosphine SCHEMBL28097689 | 0.79 | CA1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL16219562 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL28257310 | 0.74 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL15607144 | 0.72 | PADI4 (0.48) | ALDH1A1LMNAKDM4EHPGDHTT | |
| SCHEMBL18150732 | 0.72 | KDM4E (0.49) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL16783824 | 0.72 | HPGD (0.44) | ALDH1A1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL3361896 | 0.71 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2KDM4EATM | |
| SCHEMBL16843357 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL16806440 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KDM4EELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |