Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563555 | 0.98 | CA1 (0.49) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL10971690 | 0.80 | L3MBTL1 (0.54) | MAPTKDM4ECYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL8441434 | 0.80 | TTR (0.48) | MAPTKDM4EALDH1A1NPC1TNKS | |
| SCHEMBL11199697 | 0.79 | CYP1A1 (0.40) | MAPTKDM4ECYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL8784386 | 0.79 | ALDH1A1 (0.43) | CA1CA2MAPTKDM4EHPGD | |
| SCHEMBL18150732 | 0.76 | KDM4E (0.49) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL8443281 | 0.74 | ERN1 (0.49) | CA1CA2KDM4EALDH1A1CA12 | |
| SCHEMBL2474414 | 0.73 | ESR1 (0.43) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL5226658 | 0.73 | KDM4E (0.53) | CA1MAPTKDM4ECYP3A4HPGD | |
| SCHEMBL5794104 | 0.73 | MAOA (0.50) | CA1MAPTKDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960432-B | Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers | 巴斯夫欧洲公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-105960432-B | Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers | 巴斯夫欧洲公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-107922673-A | Phosphorus-containing 3-phenyl-benzofuran-2-one derivatives as stabilizers | 巴斯夫欧洲公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105960432-A | Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers | 巴斯夫欧洲公司 | 2016-09-21 | — | — | CN | disclosed |