SCHEMBL8785306

SCHEMBL8785306

CC1(c2cc(F)ccc2N)CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HDAC4 P56524 1/20 0.42
SLC6A3 Q01959 4/20 0.41
DPP4 P27487 1/20 0.40
PITRM1 Q5JRX3 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
KDM1A O60341 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
SLC6A4 P31645 3/20 0.38
PSEN1 P49768 2/20 0.38
PSEN2 P49810 2/20 0.38
APH1B Q8WW43 2/20 0.38
NCSTN Q92542 2/20 0.38
APH1A Q96BI3 2/20 0.38
PSENEN Q9NZ42 2/20 0.38
BACE1 P56817 1/20 0.38
HTR5A P47898 2/20 0.38
SLC6A2 P23975 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2568567 0.81 RARB (0.48) HDAC4SLC6A3DPP4PITRM1DPP8
SCHEMBL20628768 0.77 BACE1 (0.46) ALDH1A1HDAC4DPP4PITRM1DPP8
SCHEMBL19399062 0.77 PSEN1 (0.43) ALDH1A1HDAC4KDM1APSEN1PSEN2
SCHEMBL4059983 0.75 KDM1A (0.41) HDAC4SLC6A3KDM1ASLC6A4SLC6A2
SCHEMBL24131440 0.74 ALDH1A1 (0.42) ALDH1A1HDAC4DPP4PITRM1DPP8
SCHEMBL16409128 0.74 HDAC4 (0.39) ALDH1A1HDAC4SLC6A3DPP4PITRM1
SCHEMBL14625430 0.74 SLC6A3 (0.52) SLC6A3SLC6A4SLC6A2
SCHEMBL22400205 0.73 BACE1 (0.46) ALDH1A1HDAC4BACE1
SCHEMBL24131437 0.73 ALDH1A1 (0.45) ALDH1A1HDAC4DPP4PITRM1DPP8
SCHEMBL8785507 0.72 KDM1A (0.42) HDAC4SLC6A3KDM1ASLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623113-B1 PYRAZOLE CARBOXANILIDE FUNGICIDES MONSANTO CO (US) 1997-03-05 EP disclosed