Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385826 | 0.80 | CYP1A2 (0.46) | TSHRHTTSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL10386957 | 0.78 | CYP1A2 (0.43) | TSHRHTTSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL15198041 | 0.70 | — | — | |
| SCHEMBL25893305 | 0.69 | TSHR (0.43) | TSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13576614 | 0.67 | CYP1A2 (0.40) | GBA1CYP1A2EPHX1ALDH1A1 | |
| SCHEMBL11298915 | 0.66 | ALDH1A1 (0.43) | TSHRCYP1A2EPHX1ALDH1A1 | |
| SCHEMBL15537297 | 0.65 | CA1 (0.50) | GBA1GUSBEPHX1LSSALDH1A1 | |
| SCHEMBL22470048 | 0.63 | ALOX5 (0.53) | GBA1GUSBEPHX1ALDH1A1GLB1 | |
| SCHEMBL22668746 | 0.63 | CYP1A2 (0.47) | HTTCYP1A2EPHX1LSSALDH1A1 | |
| SCHEMBL6401737 | 0.62 | ALOX5 (0.47) | GBA1GUSBEPHX1SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143316-B2 | Method for treating peripheral vascular diseases | SUCAMPO AG (CH) | 2012-03-27 | — | — | US | disclosed |