Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787268 | 0.87 | MAOB (0.47) | MAOBAPP | |
| SCHEMBL8787004 | 0.87 | MAOB (0.64) | MAOBTNKSCYP19A1KDM4ECYP3A4 | |
| SCHEMBL8787469 | 0.76 | MAPT (0.50) | MAOBKDM4ECYP3A4ALDH1A1HPGD | |
| SCHEMBL8788292 | 0.74 | MAPK1 (0.38) | ALDH1A1HPGDHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL8787461 | 0.74 | NPC1 (0.51) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7186840 | 0.74 | TNKS (0.55) | MAOBTNKSCYP19A1KDM4ECYP3A4 | |
| SCHEMBL8787834 | 0.74 | TNKS (0.46) | MAOBTNKSCYP19A1KDM4ECYP3A4 | |
| SCHEMBL8787892 | 0.73 | MAOB (0.63) | MAOBTNKSCYP19A1KDM4ECYP3A4 | |
| SCHEMBL8788300 | 0.71 | MAPT (0.38) | MAOBKDM4ECYP3A4ALDH1A1HPGD | |
| SCHEMBL1104925 | 0.70 | APP (0.80) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |