Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | GABRP | O00591 | 3/20 | 0.55 |
| ▸ | GABRD | O14764 | 3/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.55 |
| ▸ | GABRE | P78334 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787194 | 0.82 | MAOB (0.50) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8787107 | 0.81 | TNKS (0.56) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8787004 | 0.79 | MAOB (0.64) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL3750190 | 0.78 | METAP2 (0.59) | NPC1SMN1; SMN2RAB9AHPGDTP53 | |
| SCHEMBL30307539 | 0.75 | AHR (0.68) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL5579211 | 0.75 | AHR (0.68) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8787776 | 0.75 | TNKS (0.54) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8787131 | 0.74 | MAOB (0.48) | TNKSSMN1; SMN2HPGDTNKS2CYP3A4 | |
| SCHEMBL2978295 | 0.73 | TNKS (0.55) | TNKSNPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8788229 | 0.72 | TNKS (0.58) | TNKSNPC1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212315-B1 | NOVEL CHALCONES | INDENA SPA (IT) | 2003-03-26 | — | — | EP | disclosed |
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| CN-1148593-A | Production method for chromone derivative and its medicinal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-04-30 | — | — | CN | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |