Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787000 | 0.87 | MAOB (0.64) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8788290 | 0.81 | MAOB (0.41) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL6939176 | 0.80 | NPC1 (0.65) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL5854161 | 0.77 | MIF (0.61) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL5854157 | 0.76 | MIF (0.56) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8788360 | 0.76 | MAOB (0.44) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8787469 | 0.76 | MAPT (0.50) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8787165 | 0.75 | RAB9A (0.63) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8788335 | 0.75 | GLA (0.48) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8787131 | 0.74 | MAOB (0.48) | KDM4EHPGDALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |