Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835165 | 0.84 | TSHR (0.47) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL8784877 | 0.83 | MEN1 (0.44) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL8784942 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL8785928 | 0.74 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2TSHRCYP2C19GAA | |
| SCHEMBL8786585 | 0.71 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2PDE4DTSHRCYP2C19 | |
| SCHEMBL8785879 | 0.70 | L3MBTL1 (0.49) | ALDH1A1SMN1; SMN2PDE4BTSHRMEN1 | |
| SCHEMBL19124573 | 0.70 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL30746805 | 0.69 | MEN1 (0.41) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL29173727 | 0.69 | MEN1 (0.41) | ALDH1A1SMN1; SMN2TSHRMEN1CYP1A2 | |
| SCHEMBL8784822 | 0.69 | LPAR1 (0.41) | SMN1; SMN2MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |