Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11776647 | 0.98 | PARP1 (0.61) | PARP1CASP6LMNAALDH1A1PKM | |
| SCHEMBL8349696 | 0.89 | PARP1 (0.67) | PARP1CASP6LMNAALDH1A1PKM | |
| SCHEMBL842661 | 0.87 | CASP6 (0.72) | CASP6LMNATSHRPOLBHCAR3 | |
| SCHEMBL30810715 | 0.87 | CASP6 (0.72) | CASP6LMNATSHRPOLBHCAR3 | |
| SCHEMBL145092 | 0.87 | CASP6 (0.72) | CASP6LMNATSHRPOLBHCAR3 | |
| SCHEMBL2433562 | 0.86 | CASP6 (0.66) | PARP1CASP6LMNATSHRPOLB | |
| SCHEMBL11649278 | 0.86 | CASP6 (0.70) | CASP6LMNATSHRPOLBHCAR3 | |
| Ammonia Solution, Strong SCHEMBL32680170 | 0.86 | CASP6 (0.70) | CASP6LMNATSHRPOLBHCAR3 | |
| Terephthalic Acid SCHEMBL15808957 | 0.86 | CASP6 (0.70) | CASP6LMNATSHRPOLBHCAR3 | |
| SCHEMBL11776639 | 0.85 | PARP1 (0.61) | PARP1CASP6LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551549-A | AMMONOLYSIS OF DIALKYL NITROTEREPHTHALATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-05 | — | — | US | claimed |
| EP-1636192-B9 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| EP-1636192-B1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL IND LTD (JP) | 2014-01-15 | — | — | EP | disclosed |
| EP-0508682-B1 | Antibiotic carbapenem derivatives | ZENECA LTD (GB) | 1997-07-23 | — | — | EP | disclosed |
| US-5541178-A | THIENAMYCINS | ZENECA LIMITED (GB) | 1996-07-30 | — | — | US | disclosed |
| CN-1066657-A | Antimicrobial compounds | ICI PLC (GB) | 1992-12-02 | — | — | CN | disclosed |
| WO-1992017481-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508682-A1 | Antibiotic carbapenem derivatives | ZENECA LIMITED (GB) | 1992-10-14 | — | — | EP | disclosed |
| US-4551549-A | AMMONOLYSIS OF DIALKYL NITROTEREPHTHALATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-05 | — | — | US | disclosed |
| US-4551549-A | AMMONOLYSIS OF DIALKYL NITROTEREPHTHALATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-05 | — | — | US | disclosed |
| US-4399303-A | Preparation and use of nitroterephthalamic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4399303-A | Preparation and use of nitroterephthalamic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |