SCHEMBL145092

SCHEMBL145092

O=C(O)c1ccc(C(=O)O)c([N+](=O)[O-])c1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.72
TSHR P16473 2/20 0.66
LMNA P02545 1/20 0.66
HCAR3 P49019 12/20 0.60
POLB P06746 1/20 0.57
APEX1 P27695 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30810715 1.00 CASP6 (0.72) CASP6TSHRLMNAHCAR3POLB
SCHEMBL842661 1.00 CASP6 (0.72) CASP6TSHRLMNAHCAR3POLB
SCHEMBL11649278 0.98 CASP6 (0.70) CASP6TSHRLMNAHCAR3POLB
Ammonia Solution, Strong SCHEMBL32680170 0.98 CASP6 (0.70) CASP6TSHRLMNAHCAR3POLB
Terephthalic Acid SCHEMBL15808957 0.98 CASP6 (0.70) CASP6TSHRLMNAHCAR3POLB
SCHEMBL15808913 0.92 TSHR (0.71) CASP6TSHRLMNAHCAR3POLB
SCHEMBL1633750 0.87 CASP6 (0.66) CASP6TSHRLMNAHCAR3APEX1
SCHEMBL13816483 0.87 CASP6 (0.66) CASP6TSHRLMNAHCAR3APEX1
SCHEMBL2433562 0.87 CASP6 (0.66) CASP6TSHRLMNAHCAR3POLB
SCHEMBL8787371 0.87 PARP1 (0.63) CASP6TSHRLMNAHCAR3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1952 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118079944-B Porous chromium-based composite denitration catalyst and preparation method and application thereof 山东大学 2026-05-22 CN claimed
CN-117599848-B High-stability MOFs-based non-noble metal monoatomic catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2026-05-19 CN claimed
WO-2026100858-A1 POLYMER FILM COMPRISING POLYMER NANOFIBERS LOADED WITH METAL-ORGANIC FRAMEWORKS, TRIBOELECTRIC-BASED NANOGENERATOR COMPRISING SAME, AND METHOD FOR MANUFACTURING POLYMER NANOFIBERS LOADED WITH METAL-ORGANIC FRAMEWORKS 서울대학교산학협력단 2026-05-15 WO claimed
EP-3948264-B1 NON-BLEACHING COLORIMETRIC AND FLUOROMETRIC ANALYTE DETECTION BY DEGRADATION OF SOLIDS HACH CO (US) 2026-05-06 EP claimed
US-20260066298-A1 METHOD FOR MANUFACTURING METAL-ORGANIC FRAMEWORK, METAL-ORGANIC FRAMEWORK, AND ALL-SOLID-STATE BATTERY ANODE INCLUDING THE SAME HYUNDAI MOTOR CO LTD (KR) 2026-03-05 US claimed
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
EP-4651988-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS ExxonMobil Technology and Engineering Company (US) 2025-11-26 EP claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP claimed
US-20020019430-A1 Nervous system and psychological disorders EISAI INC. 2002-02-14 US claimed
US-20020013295-A1 Naaladase inhibitors for treating amyotrophic lateral sclerosis GUILFORD PHARMACEUTICALS INC., A DELAWARE CORPORATION 2002-01-31 US claimed
WO-2001092273-A2 BENZENEDICARBOXYLIC ACID DERIVATIVES GUILFORD PHARMACEUTICALS INC. (US) 2001-12-06 WO claimed
WO-2001092274-A2 NAALADASE INHIBITORS FOR TREATING RETINAL DISORDERS AND GLAUCOMA GUILFORD PHARMACEUTICALS INC. (US) 2001-12-06 WO claimed
WO-2001091738-A2 NAALADASE INHIBITORS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS GUILFORD PHARMACEUTICALS INC. (US) 2001-12-06 WO claimed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO claimed
US-4906771-A Process for catalytic oxidation of ortho-nitroaromatic compounds to ortho-nitroaromatic acids AMOCO CORPORATION (US) 1990-03-06 US claimed
US-4551549-A AMMONOLYSIS OF DIALKYL NITROTEREPHTHALATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-05 US claimed
US-4507491-A Process for preparing 1-nitrobenzene-2-alkyloxycarbonyl-5-carboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-26 US claimed
EP-0083417-B1 PROCESS FOR MAKING 2-CARBALKOXY-5-CARBOXYNITROBENZENES HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013295-A1 Naaladase inhibitors for treating amyotrophic lateral sclerosis SMN1; SMN2, GAA, NAALAD2 CASP6 2689/4885TSHR 4825/4885LMNA 1107/4885
US-20260066298-A1 METHOD FOR MANUFACTURING METAL-ORGANIC FRAMEWORK, METAL-ORGANIC FRAMEWORK, AND ALL-SOLID-STATE BATTERY ANODE INCLUDING THE SAME TWF2, PUF60, U2AF1 CASP6 962/4885TSHR 1506/4885LMNA 1820/4885
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE CASP6 2171/4885TSHR 1726/4885LMNA 2914/4885
US-20020019430-A1 Nervous system and psychological disorders GLUL, DDC, DNPEP CASP6 855/4885TSHR 4664/4885LMNA 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.