Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PMM2 | O15305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509757 | 0.83 | MEN1 (0.43) | MEN1KMT2ADRD2DRD3CA12 | |
| SCHEMBL8788747 | 0.83 | CA12 (0.45) | MEN1KMT2ADRD2DRD3CA12 | |
| SCHEMBL8090519 | 0.83 | HTR7 (0.46) | MEN1KMT2ANPC1TP53MAPT | |
| SCHEMBL5827269 | 0.83 | MEN1 (0.43) | MEN1KMT2ADRD2DRD3CA12 | |
| SCHEMBL6508550 | 0.81 | CA12 (0.43) | MEN1KMT2ANPC1TP53MAPT | |
| SCHEMBL8789224 | 0.78 | NPC1 (0.44) | NPC1TP53MAPTTSHRNFKB1 | |
| SCHEMBL766087 | 0.77 | CFTR (0.44) | MEN1KMT2ATP53DRD2DRD3 | |
| SCHEMBL8788601 | 0.77 | CCR2 (0.42) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8790062 | 0.76 | CFTR (0.41) | MEN1KMT2ATSHRDRD2DRD3 | |
| SCHEMBL8787447 | 0.75 | HTR7 (0.40) | NPC1TP53MAPTTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |