Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963629 | 0.77 | KMT2A (0.68) | KMT2AKDM4EMEN1GAAMAPK1 | |
| SCHEMBL8791213 | 0.76 | KMT2A (0.53) | KMT2AKDM4EMEN1GAAMAPK1 | |
| SCHEMBL5717697 | 0.73 | GAA (0.66) | KMT2AKDM4EMEN1GAAHPGD | |
| SCHEMBL3867453 | 0.68 | MAPT (0.62) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8787975 | 0.67 | KMT2A (0.44) | KMT2AKDM4EMEN1GAAHPGD | |
| SCHEMBL9461214 | 0.66 | HTT (0.67) | KMT2AKDM4EMEN1GAAMAPK1 | |
| SCHEMBL8788065 | 0.66 | PKM (0.55) | GAA | |
| SCHEMBL10880388 | 0.66 | FABP4 (0.63) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL8349354 | 0.65 | KMT2A (0.58) | KMT2AKDM4EMEN1GAAMAPK1 | |
| SCHEMBL17726103 | 0.65 | KDM4E (0.51) | KDM4EHPGDHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |