Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788081 | 1.00 | MAPT (0.64) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8788070 | 1.00 | MAPT (0.64) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8787978 | 0.86 | ALDH1A1 (0.64) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8787974 | 0.86 | ALDH1A1 (0.64) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL11677558 | 0.86 | MAPT (0.67) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL11677569 | 0.86 | MAPT (0.67) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8787970 | 0.86 | ALDH1A1 (0.64) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8789030 | 0.84 | MAPT (0.52) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8789034 | 0.84 | MAPT (0.52) | MAPTLMNAALDH1A1GAAHTT | |
| SCHEMBL8789024 | 0.84 | MAPT (0.52) | MAPTLMNAALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |