Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787970 | 1.00 | ALDH1A1 (0.64) | ALDH1A1PARP1PARP15PARP10MAPT | |
| SCHEMBL8787978 | 1.00 | ALDH1A1 (0.64) | ALDH1A1PARP1PARP15PARP10MAPT | |
| SCHEMBL8788079 | 0.86 | MAPT (0.64) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL8788070 | 0.86 | MAPT (0.64) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL8788081 | 0.86 | MAPT (0.64) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL1552733 | 0.85 | PARP1 (0.75) | ALDH1A1PARP1PARP15PARP10MAPT | |
| SCHEMBL7589726 | 0.85 | PARP1 (0.75) | ALDH1A1PARP1PARP15PARP10MAPT | |
| SCHEMBL11677558 | 0.83 | MAPT (0.67) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL11677569 | 0.83 | MAPT (0.67) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL8789034 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |