Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10673383 | 0.77 | RARA (0.44) | RAB9ASMN1; SMN2NPC1MAPTRARA | |
| SCHEMBL878891 | 0.75 | CYP2A6 (0.40) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL878890 | 0.72 | CYP2C19 (0.44) | MAOBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL8972692 | 0.71 | CHAT (0.42) | MAOBALDH1A1HPGD | |
| SCHEMBL8972699 | 0.71 | CHAT (0.42) | MAOBALDH1A1HPGD | |
| SCHEMBL9776467 | 0.70 | TSHR (0.40) | MAPTSRD5A2ALDH1A1HPGD | |
| SCHEMBL10675772 | 0.67 | HDAC8 (0.37) | SMN1; SMN2HPGD | |
| SCHEMBL9125251 | 0.65 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1HDAC1MAPT | |
| SCHEMBL28631743 | 0.65 | MAPT (0.48) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL183861 | 0.64 | HCAR2 (0.39) | SMN1; SMN2HDAC1MAPTPTPN1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143465-B2 | Soluble branched triaroylbenzene-based polymer and its synthetic method | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2012-03-27 | — | — | US | disclosed |