Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790934 | 1.00 | MAPT (0.33) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL8788988 | 1.00 | MAPT (0.33) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL8788699 | 0.84 | CRBN (0.34) | MAPTPOLBALDH1A1 | |
| SCHEMBL8789386 | 0.84 | CRBN (0.34) | MAPTPOLBALDH1A1 | |
| SCHEMBL8789094 | 0.84 | CRBN (0.34) | MAPTPOLBALDH1A1 | |
| SCHEMBL8788603 | 0.74 | ALDH1A1 (0.38) | MAPTPOLBGAAALDH1A1KDM4E | |
| SCHEMBL8788472 | 0.64 | CRBN (0.31) | — | |
| SCHEMBL28424303 | 0.64 | BRD4 (0.33) | — | |
| SCHEMBL8790932 | 0.64 | CRBN (0.31) | — | |
| SCHEMBL8788986 | 0.64 | CRBN (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788796-A1 | URICOSURIC AGENT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |