SCHEMBL8788699

SCHEMBL8788699

O=C1CN(S(=O)(=O)C2CCCCC2)C(=O)N1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.34
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
OGFRL1 Q5TC84 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8789386 1.00 CRBN (0.34) CRBNALDH1A1POLBMAPTOPRM1
SCHEMBL8789094 1.00 CRBN (0.34) CRBNALDH1A1POLBMAPTOPRM1
SCHEMBL8790934 0.84 MAPT (0.33) ALDH1A1POLBMAPT
SCHEMBL8788988 0.84 MAPT (0.33) ALDH1A1POLBMAPT
SCHEMBL8788474 0.84 MAPT (0.33) ALDH1A1POLBMAPT
SCHEMBL8789424 0.72 ALDH1A1 (0.41) CRBNALDH1A1POLBMAPT
SCHEMBL8790932 0.72 CRBN (0.31) CRBN
SCHEMBL8788472 0.72 CRBN (0.31) CRBN
SCHEMBL28424303 0.72 BRD4 (0.33) CRBN
SCHEMBL8788986 0.72 CRBN (0.31) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788796-A1 URICOSURIC AGENT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-08-13 EP disclosed