Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788729 | 0.89 | EDNRA (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL8788635 | 0.89 | PPARG (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL8789150 | 0.87 | PPARG (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL8790180 | 0.87 | PPARG (0.77) | AGTR1AGTR2PPARG | |
| SCHEMBL8907873 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL8790696 | 0.83 | AGTR1 (0.78) | AGTR1AGTR2PPARG | |
| SCHEMBL8789354 | 0.82 | PPARG (0.72) | AGTR1AGTR2PPARG | |
| SCHEMBL9095608 | 0.81 | PPARG (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL8397131 | 0.81 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL8392240 | 0.81 | AGTR1 (0.80) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| EP-0468470-A1 | Benzimidazoles, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |