Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905544 | 0.89 | PPARG (0.48) | AGTR1PPARGAGTR2KDM4E | |
| SCHEMBL8905895 | 0.88 | PPARG (0.47) | AGTR1PPARGAGTR2 | |
| SCHEMBL8907871 | 0.86 | KDM4E (0.45) | AGTR1PPARGAGTR2KDM4ETDP1 | |
| SCHEMBL8788720 | 0.84 | AGTR1 (0.65) | AGTR1PPARGAGTR2 | |
| SCHEMBL8906716 | 0.83 | AGTR1 (0.53) | AGTR1PPARGAGTR2KDM4E | |
| SCHEMBL8905593 | 0.82 | PPARG (0.50) | AGTR1PPARGAGTR2KDM4E | |
| SCHEMBL8906712 | 0.81 | PPARG (0.49) | AGTR1PPARGAGTR2KDM4E | |
| SCHEMBL8906835 | 0.80 | AGTR1 (0.49) | AGTR1PPARGAGTR2 | |
| SCHEMBL8905966 | 0.80 | AGTR1 (0.47) | AGTR1PPARGAGTR2 | |
| SCHEMBL8905980 | 0.80 | PPARG (0.51) | AGTR1PPARGAGTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |