Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552408 | 0.82 | MCHR1 (0.47) | ROCK2MCHR1CCR2NOTUMROCK1 | |
| SCHEMBL8595364 | 0.81 | MCHR1 (0.47) | ROCK2MCHR1CCR2NOTUMROCK1 | |
| SCHEMBL8552381 | 0.81 | MCHR1 (0.47) | ROCK2MCHR1CCR2NOTUMROCK1 | |
| SCHEMBL9272294 | 0.81 | MCHR1 (0.41) | ROCK2MCHR1CCR2NOTUMROCK1 | |
| SCHEMBL7608380 | 0.81 | ROCK2 (0.53) | ROCK2MCHR1NOTUMROCK1HDAC6 | |
| SCHEMBL7604788 | 0.81 | ROCK2 (0.53) | ROCK2MCHR1NOTUMROCK1HDAC6 | |
| SCHEMBL6507548 | 0.81 | ROCK2 (0.53) | ROCK2MCHR1NOTUMROCK1HDAC6 | |
| SCHEMBL8554800 | 0.80 | MCHR1 (0.46) | ROCK2MCHR1CCR2NOTUMROCK1 | |
| SCHEMBL7610426 | 0.78 | MCHR1 (0.45) | ROCK2MCHR1NOTUMROCK1HDAC6 | |
| SCHEMBL7609608 | 0.78 | MCHR1 (0.45) | ROCK2MCHR1NOTUMROCK1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |