SCHEMBL8789331

SCHEMBL8789331

CCCCCN(C(=O)NC1CCCCC1)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c2c1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.55
AGTR2 P50052 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8789127 0.99 AGTR1 (0.55) AGTR1AGTR2
Water SCHEMBL8789674 0.95 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL8944787 0.92 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL8789653 0.89 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL8394522 0.88 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL8393431 0.87 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL8393689 0.87 AGTR1 (0.71) AGTR1AGTR2
SCHEMBL8392111 0.87 AGTR1 (0.71) AGTR1AGTR2
SCHEMBL9042473 0.86 AGTR1 (0.59) AGTR1AGTR2
Water SCHEMBL8394051 0.86 AGTR1 (0.54) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468470-B1 Benzimidazoles, medicaments containing them and process for their preparation THOMAE GMBH DR K (DE) 1997-04-16 EP claimed
EP-0468470-A1 Benzimidazoles, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-01-29 EP claimed