SCHEMBL8944787

SCHEMBL8944787

CCCCc1nc2ccc(N(C)C(=O)NC3CCCCC3)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.57
AGTR2 P50052 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8393431 0.95 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL8391637 0.93 AGTR1 (0.52) AGTR1AGTR2
Water SCHEMBL8394051 0.93 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL8789331 0.92 AGTR1 (0.55) AGTR1AGTR2
Water SCHEMBL8789127 0.91 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL8396768 0.87 AGTR1 (0.75) AGTR1AGTR2
SCHEMBL8393836 0.87 AGTR1 (0.75) AGTR1AGTR2
Water SCHEMBL8789674 0.86 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL8394877 0.86 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL7309365 0.85 AGTR1 (0.48) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US claimed