SCHEMBL8789690

SCHEMBL8789690

CC1(C)CC(NCCCNCCNCCCNC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.43
GAA P10253 4/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RECQL P46063 1/20 0.38
POLB P06746 1/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 3/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
RAD52 P43351 1/20 0.33
GFER P55789 1/20 0.33
EZH2 Q15910 1/20 0.33
KDM1A O60341 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10638103 0.98 SLC2A1 (0.44) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL10643257 0.98 SLC2A1 (0.44) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL10644037 0.98 SLC2A1 (0.44) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL8762446 0.92 GAA (0.47) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL10938455 0.92 CASP2 (0.42) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL11235208 0.91 SLC2A1 (0.40) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL9023360 0.90 GAA (0.46) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL10637656 0.90 GAA (0.46) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL10937048 0.90 SLC2A1 (0.40) SLC2A1GAAKDM4ELMNAALDH1A1
SCHEMBL11210685 0.89 KMT2A (0.41) SLC2A1GAAKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5652364-A REACTION OF CYANURIC CHLORIDE WITH ALKANOLS OR ALKOXIDES FOLLOWED BY REACTION WITH TETRAMETHYL-4-PIPERIDINOLS CIBA-GEIGY CORPORATION (US) 1997-07-29 US disclosed
EP-0601978-B1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA GEIGY AG (CH) 1997-05-02 EP disclosed
US-5610211-A 2,2,6,6-tetramethylpiperidine derivatives for use as stabilizing agents for organic materials CIBA-GEIGY CORPORATION (US) 1997-03-11 US disclosed
EP-0601978-A1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA-GEIGY AG (CH) 1994-06-15 EP disclosed