Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789973 | 1.00 | BCHE (0.57) | BCHEACHECYP19A1KCNH2 | |
| SCHEMBL8790071 | 0.87 | CYP19A1 (0.54) | BCHEACHECYP19A1 | |
| SCHEMBL8790080 | 0.87 | CYP19A1 (0.54) | BCHEACHECYP19A1 | |
| SCHEMBL8790222 | 0.82 | PTGS2 (0.60) | BCHEACHECYP19A1KCNH2 | |
| SCHEMBL8790218 | 0.82 | PTGS2 (0.60) | BCHEACHECYP19A1KCNH2 | |
| SCHEMBL3147612 | 0.82 | CYP19A1 (0.65) | BCHEACHECYP19A1 | |
| SCHEMBL8790306 | 0.79 | CYP19A1 (0.61) | BCHEACHECYP19A1 | |
| SCHEMBL8789804 | 0.77 | CYP19A1 (0.67) | CYP19A1 | |
| SCHEMBL15903365 | 0.75 | CYP19A1 (0.69) | CYP19A1 | |
| SCHEMBL8789870 | 0.75 | CYP19A1 (0.63) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-B1 | ACRIDINE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-28 | — | — | EP | disclosed |
| US-5604237-A | IMPROVE OR INCREASE EFFICACY OF ANTITUMOR AGENT, INCREASE OR RESTORE SENSITIVITY OF TUMOR TO ANTITUMOR AGENT, REVERSE OR REDUCE RESISTANCE OF TUMOR TO ANTITUMOR AGENT | LABORATOIRES GLAXO SA (FR) | 1997-02-18 | — | — | US | disclosed |