Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790222 | 1.00 | PTGS2 (0.60) | PTGS2CYP19A1ACHEBCHEMMP1 | |
| SCHEMBL8836082 | 0.88 | ACHE (0.52) | PTGS2CYP19A1ACHEKCNH2MAPT | |
| SCHEMBL8836079 | 0.88 | ACHE (0.52) | PTGS2CYP19A1ACHEKCNH2MAPT | |
| SCHEMBL3143902 | 0.84 | ACHE (0.65) | PTGS2CYP19A1ACHEBCHEKCNH2 | |
| SCHEMBL9827777 | 0.83 | PTGS2 (0.68) | PTGS2CYP19A1MMP1TLR9MAPT | |
| SCHEMBL9827783 | 0.83 | PTGS2 (0.68) | PTGS2CYP19A1MMP1TLR9MAPT | |
| SCHEMBL8789973 | 0.82 | BCHE (0.57) | CYP19A1ACHEBCHEKCNH2 | |
| SCHEMBL8789969 | 0.82 | BCHE (0.57) | CYP19A1ACHEBCHEKCNH2 | |
| SCHEMBL19249417 | 0.81 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL19249402 | 0.80 | KCNH2 (0.62) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-B1 | ACRIDINE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-28 | — | — | EP | disclosed |
| US-5604237-A | IMPROVE OR INCREASE EFFICACY OF ANTITUMOR AGENT, INCREASE OR RESTORE SENSITIVITY OF TUMOR TO ANTITUMOR AGENT, REVERSE OR REDUCE RESISTANCE OF TUMOR TO ANTITUMOR AGENT | LABORATOIRES GLAXO SA (FR) | 1997-02-18 | — | — | US | disclosed |