Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 4/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789835 | 0.86 | ESR1 (0.47) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8789330 | 0.85 | CCNB2 (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL7692326 | 0.85 | ESR1 (0.43) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8790260 | 0.81 | ESR1 (0.39) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9356958 | 0.81 | NR1I2 (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8792445 | 0.81 | CCNB2 (0.38) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8789669 | 0.80 | NR1I2 (0.32) | NR1I2 | |
| SCHEMBL8790282 | 0.79 | CCNB2 (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8789363 | 0.78 | MAPK1 (0.36) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL9027686 | 0.78 | ALDH1A1 (0.39) | CCNB2CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772591-A1 | 2-PHENYL INDOLES AS ANTI-OESTROGEN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-14 | — | — | EP | claimed |
| WO-1996003375-A1 | 2-PHENYL INDOLES AS ANTI-OESTROGEN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | claimed |
| EP-0772591-A1 | 2-PHENYL INDOLES AS ANTI-OESTROGEN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003375-A1 | 2-PHENYL INDOLES AS ANTI-OESTROGEN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |