SCHEMBL879048

SCHEMBL879048

COc1cc(C)c(-c2cccc(O)c2)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 6/20 0.48
FYN P06241 5/20 0.46
HSD17B1 P14061 5/20 0.45
KDM1A O60341 1/20 0.44
MAOA P21397 1/20 0.44
ESR2 Q92731 2/20 0.43
BMPR1A P36894 1/20 0.43
TGFBR1 P36897 1/20 0.43
ACVRL1 P37023 1/20 0.43
ACVR1 Q04771 1/20 0.43
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
ESR1 P03372 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP2C8 P10632 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP4B1 P13584 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10190449 0.81 MGAM (0.53) FYNHSD17B1ESR2ESR1MGAM
SCHEMBL30112758 0.80 CYP3A4 (0.52) HSD17B2FYNHSD17B1KDM1AMAOA
SCHEMBL28588012 0.80 ESR2 (0.46) MAOAESR2GAA
SCHEMBL29431753 0.79 KDM1A (0.57) HSD17B2FYNHSD17B1KDM1AMAOA
SCHEMBL1029074 0.77 HTR7 (0.55) FYNKDM1AMAOAESR2CYP3A4
SCHEMBL16710403 0.77 FYN (0.49) HSD17B2FYNHSD17B1KDM1AMAOA
SCHEMBL10306739 0.74 HSD17B1 (0.54) HSD17B2HSD17B1ESR2CYP3A4CYP2C9
SCHEMBL6536009 0.73 FYN (0.52) HSD17B2FYNHSD17B1KDM1AMAOA
SCHEMBL12326171 0.73 TAAR1 (0.48) GAA
SCHEMBL1805780 0.71 ESR2 (0.59) HSD17B1ESR2ESR1POLHMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed