Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.43 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793375 | 0.93 | ADRB3 (0.49) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8790987 | 0.93 | ADRB2 (0.46) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8790660 | 0.93 | ADRB2 (0.45) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8791814 | 0.93 | ADRB2 (0.45) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8791415 | 0.92 | ADRB2 (0.46) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8791244 | 0.91 | ADRB2 (0.48) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8792061 | 0.89 | ADRB3 (0.42) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8792006 | 0.89 | ADRB2 (0.47) | ADRB2SERPINE1ADRB1ADRB3CCR2 | |
| SCHEMBL8791862 | 0.89 | ADRB3 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8792628 | 0.87 | ADRB2 (0.39) | ADRB2SERPINE1ADRB1ADRB3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703911-B1 | SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | PFIZER (US) | 1997-07-02 | — | — | EP | disclosed |