Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.41 |
| ▸ | CCR2 | P41597 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792020 | 0.94 | ADRB2 (0.44) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8791862 | 0.94 | ADRB3 (0.48) | ADRB2ADRB3ADRB1 | |
| SCHEMBL8791149 | 0.94 | ADRB2 (0.44) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8790482 | 0.93 | ADRB2 (0.46) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8791521 | 0.92 | ADRB2 (0.46) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8791999 | 0.91 | ADRB2 (0.48) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8792490 | 0.90 | ADRB2 (0.48) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8791830 | 0.90 | ADRB2 (0.42) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8793375 | 0.88 | ADRB3 (0.49) | ADRB2ADRB3ADRB1 | |
| SCHEMBL8791326 | 0.88 | ADRB2 (0.41) | ADRB2SERPINE1ADRB3ADRB1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703911-B1 | SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | PFIZER (US) | 1997-07-02 | — | — | EP | disclosed |